The Gene Wars ; Science, Politics, and the Human Genome Robert
Cook-Deegan
Chronology Genesis of the Human
Genome Project
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Russian, genome research in, p. 190-95,
211:
Russian participation in the Human
Genome Project got
off to a rocky start.
The instigator of the Russian
program was Alexander Bayev, who was in exile from Russia
when Watson and Crick published their work on the structure of DNA. The USSR
had few scientists who could appreciate the achievements of molecular biology.
In the 1960s, with the effort of Bayev’s mentor,
Vladimir Englehardt, molecular biology became an accepted
discipline.
One of Bayev’s
students, Andrei Mirzabekov, was permitted to study
in the West, and became
a link between the USSR and world molecular biology.
Through the 1970s and 80s,
Bayev and Mirzabekov
continued to work at the Institute of Molecular Biology
in Moscow, now
called the Englehardt
institute.
Bayev and Mirzabekov became the
champions of the USSR
genome project in 1986. The project benefited from the new Gorbachev policies
of glasnost (openness) and perestroika (restructuring of science
including biotechnology to national economic goals). The first step was to bring
soviet molecular biology up to world class standards. A soviet genome project
met opposition in the Russian
Academy of Sciences until
1989. Then it got more support, but was again threatened, but spared, in the
hard transition from a communist to a capitalist economy. Although science
declined through 1992, the genome program was given a budget under the Russian Academy of Sciences, and was relatively
well off.
In summary, the Russian National
Genome Program was constantly struggling to keep up with world standards.